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| ID | Type | Description | Link |
|---|---|---|---|
| 1R01DC013767-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Deafness and Other Communication Disorders (NIDCD) | NIH |
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Over a 5 year period infant and baby siblings of children with autism spectrum disorders (ASD) will be recruited to this study and will be randomized into 2 groups. Parents of the intervention group will receive 12 weeks of coaching in how to implement this intervention. Parents randomized to the control group will not receive intervention coaching. Both groups will attend a series of clinic appointments for data collection that occur at 3 month intervals over a 9 month period.
This two-site randomized controlled trail (RCT) will include a sample of 80 siblings of children with ASD (Sibs-ASD) (11 months, 15 days to 18 months, 15 days) who are stratified on initial cumulative-risk status for communication disorder and then randomly assigned to Ingersoll's Improving Parents As Communication Teachers (ImPACT; Ingersoll & Dvortcsak, 2010) treatment or to a business-as-usual (BAU) control condition. The following hypotheses will be tested:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Impact Parent Training | Experimental | Parents receive 22 1.5-hour sessions with a Speech Language pathologist coaching them in the implementation of the Impact intervention |
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| No Impact | Placebo Comparator | No parent coaching is provided |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Impact Parent Training | Behavioral |
| ||
| No Impact |
| Measure | Description | Time Frame |
|---|---|---|
| Growth in communication | weighted frequency of intentional communication from the Communication and Symbolic Behavior Scale, high is good range is 0 - 400 | Change between baseline and 9 months after entry |
| Measure | Description | Time Frame |
|---|---|---|
| Growth in play | raw scores from Developmental Play Assessment, high is good, range is 0 to 50 | Change from Baseline to 9 months after entry |
| Motor imitation | raw scores from the Structured Social Imitation Scale, high is good, range 0 - 50 |
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Inclusion Criteria:
Younger sibling of a child with ASD -
Exclusions:
No primary motor impairment. No feeding tubes. No other neurological or genetic conditions. Primary language exposure: The primary parent speak to the child using English 50% of the time, and process.
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| Name | Affiliation | Role |
|---|---|---|
| Paul J. Yoder, Ph.D. | Vanderbilt University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Vanderbilt University | Nashville | Tennessee | 37232 | United States | ||
| University of Washington |
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| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| ID | Term |
|---|---|
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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The assessors and coders are blind to treatment assignment. This will be achieved by using different people to conduct the treatment vs assessment and coding. Additionally, these different staff members have offices on different floors.
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| Change from Baseline to 9 months after entry |
| Autism social affect symptomatology | average of z score from raw scores from Communication and Symbolic Behavior Scale and Autism Diagnositic Observation Schedule (reflected) if they are correlated > .4, after reflection high is good, -4 to 4 | 9 months after entry |
| Language delay | average of z scores from standard scores or percentile rankings from MacAuthur Communication Development Index and Mullen Scale of Early Learning if they are correlated above .4, high is good, range is -4 to 4 | 9 months after entry |
| language level | average of time 4-referenced z scores from raw scores from Communication and Symbolic Behavior Scales, Brief Observation of Social Communication Change, and MacArthur Communication Development Index if they are correlated above .4, High is good, -4 to 4 | Change from baseline to 9 mos after treatment ends |
| parent implementation of ImPACT treatment | fidelity of treatment of aspects of ImPACT treatment from PCS and PCFP | change from baseline to immediately post-treatment |
| Seattle |
| Washington |
| 98195-7920 |
| United States |