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This study aims to analyze whether serum Progsterone levels on the day of Embryo Transfer are related with Ongoing Pregnancy rate in artificial endometrial preparation cycles with intravaginal micronized progesterone.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Analysis of serum Progesterone in blood sample | Diagnostic Test | Levels of progesterone will be determined on the day of embryo transfer in patients undergoing artificial endometrial preparation cycles. |
| Measure | Description | Time Frame |
|---|---|---|
| Concentration of serum Progesterone levels | Serum progesterone levels | The day of embryo transfer |
| Ongoing Pregnancies depending on Progesterone levels ranges. | Ultrasound to confirm Ongoing Pregnancy | Week 5-12 after Embryo Transfer |
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Inclusion Criteria
Age <50 years old
Hormonal Replacement therapy cycle for embryo transfer in any of the following situations:
Endometrial line: >6.5-7mm (with trilaminar aspect) in proliferative phase, before introducing progesterone.
Administration of natural micronized progesterone intravaginally (400 mg/12 hours for 5 complete days (10 dosis), before the embryo transfer and maintained until pregnancy week 12.
Embryo transfer of blastocyst (day 5-6).
Signed Informed Consent
Exclusion Criteria
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Women who are undergoing IVF treatments with artificial endometrial preparation with hormonal replacement therapy.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto Valenciano de Infertilidad Spain | Valencia | 46015 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33340402 | Derived | Labarta E, Mariani G, Paolelli S, Rodriguez-Varela C, Vidal C, Giles J, Bellver J, Cruz F, Marzal A, Celada P, Olmo I, Alama P, Remohi J, Bosch E. Impact of low serum progesterone levels on the day of embryo transfer on pregnancy outcome: a prospective cohort study in artificial cycles with vaginal progesterone. Hum Reprod. 2021 Feb 18;36(3):683-692. doi: 10.1093/humrep/deaa322. |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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Serum
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |