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The purpose of this study is to determine whether providing individuals with personalized information on cellular aging, including telomere length, will stimulate them to adhere to cardiac prevention strategies and improve exercise capacity.
Individuals who have sustained a heart attack are at considerable risk for future cardiac events. A cardiac rehabilitation and exercise program can reduce this risk but it remains a challenge to adopt optimum lifestyle changes. We will determine whether providing individuals with information on leukocyte telomere length, will motivate them to improve their exercise performance. We will test whether professionally conveying this information will stimulate an individual to adhere to proven cardiac prevention strategies, looking at the extent to which one's exercise capacity improves over time.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | Participants receive standard care in cardiac rehabilitation program | |
| Knowledge transfer group | Experimental | Participants receive standard care in cardiac rehabilitation program plus education regarding telomere length |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Education regarding telomere length | Behavioral | Teaching concepts of cellular aging and telomere length |
|
| Measure | Description | Time Frame |
|---|---|---|
| Exercise capacity based on cardiopulmonary exercise testing | Online VO2 maximum | after 6-month cardiac rehabilitation program |
| Measure | Description | Time Frame |
|---|---|---|
| Adherence to supervised exercise sessions | Proportion of prescribed supervised on-site exercise sessions attended | 6 months |
| Activity assessment | Garmin recording |
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Inclusion Criteria:
1. Individuals who have sustained a myocardial infarction and entered the cardiac rehabilitation program
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| J. Geoffrey Pickering, MD PhD | Western Faculty | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| London Health Sciences Centre, Western University | London | Ontario | N6A 5A5 | Canada |
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| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| 6 months |
| D007238 |
| Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |