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| Name | Class |
|---|---|
| Geistlich Pharma AG | INDUSTRY |
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The aim of this study is to evaluate the additional effect of antimicrobial photodynamic therapy regeneration treatment of mandibular furcation lesions when associated to bovine bone and porcine collagen membrane.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Active Comparator | Decontamination of furcation defect with scaling and root planing only. |
|
| Antimicrobial Photodynamic Therapy | Experimental | Decontamination of furcation defect with scaling and root planing complemented by antimicrobial photodynamic therapy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Scaling and root planing | Procedure | Furcation treatment by scaling and root planing |
|
| Measure | Description | Time Frame |
|---|---|---|
| Horizontal probing depth | Measured with a periodontal probe (mm). Ideal if 0. | one year |
| Tomographic Bone filling | Complete filling of furcation defect in tomographic images. Ideal is a radiopaque image similar to neighbor bone. | One year |
| Measure | Description | Time Frame |
|---|---|---|
| Probing depth | Distance from gingival margin to bottom of sulcus. Measured with a periodontal probe (mm). Ideal if < 2 mm. | one year |
| Clinical Attachment Level | Distance from cemento-enamel junction to bottom of sulcus. Measured with a periodontal probe (mm). Ideal if < 2 mm. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bauru School of Dentistry | Bauru | São Paulo | 17012-901 | Brazil | ||
| Bauru School of Dentistry |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23731242 | Background | Luchesi VH, Pimentel SP, Kolbe MF, Ribeiro FV, Casarin RC, Nociti FH Jr, Sallum EA, Casati MZ. Photodynamic therapy in the treatment of class II furcation: a randomized controlled clinical trial. J Clin Periodontol. 2013 Aug;40(8):781-8. doi: 10.1111/jcpe.12121. Epub 2013 Jun 3. | |
| 25644295 | Background | Avila-Ortiz G, De Buitrago JG, Reddy MS. Periodontal regeneration - furcation defects: a systematic review from the AAP Regeneration Workshop. J Periodontol. 2015 Feb;86(2 Suppl):S108-30. doi: 10.1902/jop.2015.130677. |
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| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| D010510 | Periodontal Diseases |
| D016301 | Alveolar Bone Loss |
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D002908 | Chronic Disease |
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| ID | Term |
|---|---|
| D014080 | Tooth Exfoliation |
| D016745 | Root Planing |
| D014048 | Tolonium Chloride |
| ID | Term |
|---|---|
| D009063 | Dental Physiological Phenomena |
| D055688 | Digestive System and Oral Physiological Phenomena |
| D012534 | Dental Scaling |
| D003777 | Dental Prophylaxis |
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Split-mouth design. One side of mouth is test and the other is control side.
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| Toluidine Blue O | Drug | Antimicrobial photodynamic therapy with toluidine blue O (10mg/ml) and red laser. |
|
|
| one year |
| Bleeding on probing | Visual confirmation of bleeding after probing. Ideal if not bleeding. | One year |
| Bauru |
| Brazil |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001862 | Bone Resorption |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D055093 | Periodontal Atrophy |
| D010517 | Periodontics |
| D003813 | Dentistry |
| D013357 | Subgingival Curettage |
| D011313 | Preventive Dentistry |
| D010640 | Phenothiazines |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
| D006575 | Heterocyclic Compounds, 3-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |