Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Knee Pain

Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Knee Pain

The aim of this study is to investigate brain response and connectivity changes evoked by video-guided acupuncture imagery treatment (VGAIT) and verum and sham acupuncture in knee osteoarthritis patients to elucidate the underlying brain mechanisms of mind-body interaction, imagery, and acupuncture.

Inclusion Criteria:

• Right-handed
• Knee osteoarthritis patients
• Ages 40 to 70 years old

Exclusion Criteria:

• Any contraindications to MRI scanning (claustrophobia, metal implants)
• Current or past history of major medical, neurological, or psychiatric illness other than knee osteoarthritis (including high blood pressure, heart disorders, impaired elimination, stomach problems, major kidney or liver problems, bleeding problems, severe dehydration, history of diabetes, history of asthma or other respiratory condition)
• Pregnancy
• Non fluent English speaker