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Investigators aim to investigate whether circulating tumor DNA is a sensitive marker to evaluate patients' response to neoadjuvant chemotherapy
Neoadjuvant chemotherapy(NAC) is traditionally for locally advanced disease, converting an inoperable to a resectable tumor.In recent years, it has become an option for patients of lower tumor stage to increase the possibility of breast conserving therapy. An effective method to monitor the response to NAC is important.
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| Measure | Description | Time Frame |
|---|---|---|
| death of breast cancer | The event is defined as death of breast cancer, which is a separate measure | Follow-up time is estimated to be up to 5 years. The duration is from the date of diagnosis to date of death of breast cancer or date of death of any cause, whichever come first. |
| Measure | Description | Time Frame |
|---|---|---|
| tumor recurrence or distant metastasis | The event is defined as breast cancer local recurrence or distant metastasis | Follow-up time is estimated to be up to 5 years.The duration is from diagnosis to local recurrence or distant metastasis of breast cancer. Patients were followed up every six months in first three years, then followed up once a year. |
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Inclusion Criteria:
Exclusion Criteria:
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Breast cancer patient receiving NAC
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shunying Li | Contact | +86-15915939702 | lishunying@foxmail.com |
| Name | Affiliation | Role |
|---|---|---|
| qiang Liu | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sunyat-sen Memorial Hospital | Recruiting | Guandong | Guangdong | China |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| D017437 |
| Skin and Connective Tissue Diseases |