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Epidural, Combined Spinal-Epidural, and more recently dural puncture epidural are forms of neuraxial anesthesia used to provide pain relief in laboring women . The investigators want to assess the onset of pain relief with 2 different neuraxial techniques performed at our center, but which have not yet been compared in the literature: (1) Modified CSE, with only local anesthetic injected into the spinal fluid to reduce side effects of opioids that are seen with the traditional CSE and (2) Dural Puncture Epidural (DPE), involving puncture of the spinal membrane, but without injection of medication into the spinal space. The investigators hypothesize that the onset of labor analgesia will be faster with modified CSE compared to DPE.
Purpose of the research:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Modified CSE | Experimental | MCSE group: 1 ml of 0.25% bupivacaine will be injected intrathecally |
|
| Dural puncture epidural | Active Comparator | Dural puncture performed with a spinal needle, but no medication will be injected intrathecally. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Modified CSE | Procedure | MCSE group: 1 ml of 0.25% bupivacaine will be injected intrathecally |
|
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of the onset of effective analgesia between the study techniques | Numerical Rating Scale (NRS) for pain \ | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of block quality between the study techniques | Time to T10 sensory block in minutes will be measured | 1 year |
| Comparison of the incidence of pruritus between the study techniques | Participants will be assessed for pruritus every hour, by grading the severity on a scale ranging from 0-3; 0 = none, 1 = mild, 2= moderate and 3 = severe |
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Inclusion Criteria:
Exclusion Criteria:
Pregnant patients
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yamini Subramani, MD | Contact | 519-902-4715 | yaminisrs@rediffmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Indu Singh, MD, FRCPC | Western University | Principal Investigator |
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| Dural puncture epidural | Procedure | DPE group: Dural puncture performed, but no medication will be injected intrathecally. |
|
| 1 year |
| Comparison of the incidence of fetal bradycardia between the study techniques | Fetal bradycardia is defined as a fetal heart rate of less than 100 beats per minute, persisting for more than 1 minute. | 1 year |