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Blood Pressure Lowering Effects of Amosartan Regarding Proviso in Patients with Hypertension
After taking Amozatan (AMS, amlodipine / rozanthin combination) in patients with essential hypertension, the percentage of patients who reached the mean systolic target blood pressure was evaluated
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Amosartan | Drug | amosartan is a combination of amlodipine, which is a calcium channel blocker (CCB), and rozatan, an angiotensin II receptor antagonist (ARB), and is an antihypertensive agent |
| Measure | Description | Time Frame |
|---|---|---|
| Patients with essential hypertension evaluated the mean blood pressure after taking amosartan. | Blood Pressure Lowering Effects of Amosartan Regarding Proviso in Patients with Hypertension | 6 month |
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Inclusion Criteria:
Exclusion Criteria:
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Estimated total number of patients: 3,150 Estimated number of centers: 37
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22035131 | Background | Kim SH, Ryu KH, Lee NH, Kang JH, Kim WS, Park SW, Lee HY, Kim JJ, Ahn YK, Suh SY. Efficacy of fixed-dose amlodipine and losartan combination compared with amlodipine monotherapy in stage 2 hypertension: a randomized, double blind, multicenter study. BMC Res Notes. 2011 Oct 28;4:461. doi: 10.1186/1756-0500-4-461. | |
| 12829555 | Background |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| Law MR, Wald NJ, Morris JK, Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ. 2003 Jun 28;326(7404):1427. doi: 10.1136/bmj.326.7404.1427. |
| 19387578 | Background | Choi SM, Seo MJ, Kang KK, Kim JH, Ahn BO, Yoo M. Beneficial effects of the combination of amlodipine and losartan for lowering blood pressure in spontaneously hypertensive rats. Arch Pharm Res. 2009 Mar;32(3):353-8. doi: 10.1007/s12272-009-1307-x. Epub 2009 Apr 23. |