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Initial difficulties recruiting + main researcher had to withdraw from the study
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| Name | Class |
|---|---|
| University of Glasgow | OTHER |
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The main aim of this study is to investigate the effect of patterned distribution stimulation compared to conventional stimulation in reducing muscle fatigue during functional electrical stimulation (FES) following spinal cord injury (SCI).
Functional electrical stimulation (FES) is a commonly used technique in rehabilitation and often associated with rapid muscle fatigue which becomes the limiting factor in its applications. The main objective of this study is to investigate the effects on the onset of fatigue of conventional synchronous stimulation, as well as asynchronous stimulation that mimic voluntary muscle activation targeting different motor units which are activated sequentially or randomly via multiple pairs of stimulation electrodes. Three different approaches with various electrode configurations will be investigated, as well as different patterns of stimulation applied to the gastrocnemius muscle. In addition, the muscle changes during different patterns of stimulation will be evaluated in this study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A: CSS & AsynS | Experimental | Electrical stimulation training on both legs: Conventional synchronous stimulation (CSS) and Asynchronous Sequential Stimulation (ASynS) - CSS/ASynS |
|
| Group B: CSS & AsynR | Experimental | Electrical stimulation training on both legs: Conventional synchronous stimulation (CSS) and Asynchronous Random Stimulation (ASynR) - CSS/ASynR |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CSS/AsynS | Procedure | 16 sessions of training over a 4 week period consisting of repeated intermittent electrical stimulation (300ms On and 700ms Off stimulation) for 10 - 30 minutes. Conventional synchronous stimulation (CSS) on one leg; Asynchronous Sequential Stimulation (ASynS) on the other leg |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle contraction ability | Change in torque produced during muscle contraction | Baseline to 6 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Normalized Fatigue Index (NFI) | Change in score on Normalized Fatigue Index (NFI) | Baseline to 6 weeks |
| Fatigue Time Interval (FTI) | Change in Fatigue Time Interval (FTI) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Henrik Gollee, DipIng PhD | University of Glasgow | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Queen Elizabeth National Spinal Injuries Unit | Glasgow | United Kingdom |
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| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
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|
| CSS/AsynR | Procedure | 16 sessions of training over a 4 week period consisting of repeated intermittent electrical stimulation (300ms On and 700ms Off stimulation) for 10 - 30 minutes. Conventional synchronous stimulation (CSS) on one leg; Asynchronous Random Stimulation (ASynR) on the other leg. |
|
| Baseline to 6 weeks |
| Twitch-Tetanus Ratio response (ΔTTR) | Change in Twitch-Tetanus Ratio response (ΔTTR) | Baseline to 6 weeks |
| D014947 | Wounds and Injuries |