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| Name | Class |
|---|---|
| Peking Union Medical College Hospital | OTHER |
| Peking University People's Hospital | OTHER |
| Peking University Cancer Hospital & Institute | OTHER |
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At present, surgical resection is still the main treatment for the potential cure of rectal cancer. Total mesorectal excision (TME) is the gold standard. The traditional laparoscopic or open surgery for some special patients is really difficult, especially for male, prostate hypertrophy, obesity, low tumor and pelvic stenosis patients to expose the gap around the mesorectum and separate to the pelvic floor. While transanal total mesorectal excision (TaTME) approach could be more directly separate the low mesorectum and relatively simple to complete distal rectal transection, which would bring some considerable advantages. Although active learning from abroad, laparoscopic assisted TaTME surgery is now in its infancy in China. It is urgent for clinical studies to obtain the results in China. This multicenter, observational study will help to encourage research in this field and to obtain data on the safety and efficacy of this procedure in Chinese patients with rectal cancer.
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| Measure | Description | Time Frame |
|---|---|---|
| Positive rate of circumferential resection margin (CRM) of the specimens | Circumferential resection margin (CRM) is the distance between the deepest point of tumor in the primary cancer and the margin of resection in the retroperitoneum or mesentery by pathological examination. CRM 0-1mm is defined as positive, while >1mm is negative. | 10 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| The grade score of the specimens integrity | shows the quality of the specimens: grade 1 is bad gross specimen which means incomplete mesorectum and pelvic fascia, and muscle layer can be see >5mm; grade 3 is high quality gross specimen, which means the specimen is cylindrical, mesorectum and pelvic fascia are complete; grade 2 is between 1and 3. | 10 days after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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lower rectal cancer patients who are suitable and willing to accept laparoscopy- assisted TME procedure and also agree with the trial
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing Friendship Hospital | Beijing | Beijing Municipality | 100050 | China |
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| ID | Term |
|---|---|
| D012004 | Rectal Neoplasms |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
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| Ruijin Hospital |
| OTHER |
| The First Hospital of Jilin University | OTHER |
| Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | OTHER |
| Liaoning Cancer Hospital & Institute | OTHER |
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| The distance between lower tumor margin and the lower reaction margin | shows the oncological safety of the surgery by pathological examination. Reports should contain the distance between lower tumor margin and the lower reaction margin. | 10 days after surgery |
| local recurrence rate | show the oncological efficacy by 3-year follow-up according to the NCCN guideline. Participants should report every follow-up examinations which prove tumor recurrence and/or metastasis or not. | 3 years after surgery |
| the operative time | preoperative safety containing operation information, complication information. | 30 days after surgery |
| postoperative hospital stay | recovery information. | 3 year after surgery |
| the score of postoperative life | quality of life contains two scales: Wexner scale and EORTC QLQ-CR29 scale, which show quality of life and the anal function. | 6 months after surgery |
| disease free survival rate | show the oncological efficacy by 3-year follow-up according to the NCCN guideline. Participants should report every follow-up examinations which prove tumor recurrence and/or metastasis or not. | 3-year after surgery |
| overall survival rate | show the oncological efficacy by 3-year follow-up according to the NCCN guideline. Participants should report every follow-up examinations which prove tumor recurrence and/or metastasis or not. | 3-year after surgery |
| the rate of postoperative complications | preoperative safety containing operation information, complication information. | 30 days after surgery |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |