This study is a non-blinded randomized controlled trial comparing the use of a preoperative "mini" block plus postoperative local infiltration of Exparel (liposomal form of bupivacaine) versus a partial single shot nerve block in subjects undergoing primary reverse or total shoulder arthroplasty to see which is more effective in controlling surgery related pain. To do so, we will utilize the Visual Analog Scale (VAS) to measure pain intensity. Opioid consumption will be recorded on a Pain Monitoring Sheet.

Inclusion Criteria:

• All individuals undergoing primary reverse and total shoulder arthroplasty by the shoulder service at Thomas Jefferson University Hospital, Methodist Hospital or Rothman Specialty Hospital.

Exclusion Criteria:

• Psychiatric illness as defined by co-morbid diagnosis of bipolar disorder or schizophrenia
• Revision arthroplasty or arthroplasty for fracture
• Unable/unwilling to consent for enrollment
• Unable to complete postoperative pain survey
• Known adverse drug reaction or allergy to the medications used
• Chronic pain syndromes (including reflex sympathetic dystrophy, fibromyalgia, chronic diffuse musculoskeletal pain)
• Patients taking long acting opioid pain medications (including extended release opioid pain medications and methadone)
• Patients under the age of 18 years
• Patients with history of hepatic disease
• Pregnant or breastfeeding women.