Tailored PCA Based on Preoperative Pain Sensitivity

The Effectiveness of Tailored Patient Controlled Analgesia Based on Preoperative Pain Sensitivity in Gynecological Patients

Opioids via intravenous patient-controlled analgesia (IV PCA) are widely used for postoperative pain control. However, effective pain control with minimized side effects of analgesic agents is still challenging. Several studies reported that preoperative pain sensitivity measured by quantitative sensory test could predict postoperative pain. Therefore, the investigators planned this trial to evaluate the effectiveness of tailored patient-controlled analgesia based on preoperative pain sensitivity measured by pressure pain threshold in patients undergoing gynecological surgery.

Inclusion Criteria:

• patients scheduled to undergo elective gynecological surgery under general anesthesia
• patients scheduled to use IV PCA for postoperative analgesia
• patients with American Society of Anesthesiologists (ASA) physical status classification I, II, III

Exclusion Criteria:

• contraindication to fentanyl use
• inability to communication
• age less than 18 years, or more than 80 years
• body weight less than 40kg, or more than 90kg
• morbid cardiovascular disease
• pregnancy