Fibrin Sealant in Esophageal Surgery

Autologous Activated Fibrin Sealant for the Esophageal Anastomosis, a Feasibility Study

Anastomotic leakage remains a major complication after esophageal surgery. Amongst other preventive measures, fibrin sealant is a promising adjunct to conventional anastomotic techniques. The investigators aimed to investigate feasibility of additional sealing by means of autologous fibrin sealant of the esophageal anastomosis.

Inclusion Criteria:

• Aged 18 - 90 years
• Scheduled to undergo elective minimal invasive esophageal surgery with thoracic or cervical anastomosis (i.e. Ivor Lewis, Orringer or McKeown esophagectomy).
• physical status (American Society of Anesthesiologists) of 3 or lower

Exclusion Criteria:

• Other malignancies
• Previous esophageal surgery were excluded