The study aimed to determine the thrombotic effects of YSS compared with salmon among healthy overweight subjects. It hypothesized that YSS may result significant, favorable thrombotic effects and the effects may be similar with salmon.

The project was a randomized, two-period, crossover trial with 8-week treatment periods and 8-week washout period. A total of 50 healthy overweight adults were recruited among staff and students in UPM. All the subjects were randomized into two groups. Each group was served with either cooked YSS (~265 g/ day) or salmon (~246 g/day) thrice per week. Blood and urine samples were collected for laboratory assessment.

Inclusion Criteria:

• Malaysian
• Overweight participants (BMI 23-27.4 kg/m2)

Exclusion Criteria:

• Regular use of fish oil supplements during the last one month
• Regular consumption of fish twice or more per week
• Vegetarian who excluded all meat, fish, and poultry from their diet
• Diagnosed with cardiovascular disease, haemostasis disorder, inflammatory disease, diabetes mellitus, hypertension, or other significant medical history that may prohibits the participation
• Receiving warfarin or aspirin treatment, or medication to lower serum lipids, blood pressure, and inflammation
• Women who are menopause, pregnant or lactating