Chinese Observational Prospective Study of Aging Population With Chronic Kidney Disease(C-OPTION)

Chinese Observational Prospective Study of Aging Population With Chronic Kidney Disease(C-OPTION)

The study is an observational, multicenter, prospective cohort study aimed at evaluating a 5-year screening programme for chronic kidney disease(CKD) in a population of elderly patients, aged 65 years or more, in China.To analyze the etiology and composition spectrum, the incidence of complications and co-morbidities.To assess the correlation between daily living ability, mental and physical function, quality of life, nutritional status and prognosis.To develop biomarkers of renal aging.

Inclusion Criteria:

• age≥65 years
• clinical diagnosis of CKD
• signed informed consent

Exclusion Criteria:

• subjects who have a poor compliance and cannot be scheduled for follow-up
• subjects participating in other interventional clinical trials
• ESRD or dialysis
• Acute kidney injury(AKI)
• history of solid organ or bone marrow transplantation
• active malignancy within 24 months prior to screening or metastatic cancer
• life expectancy less than 6 months；
• severe cognitive impairment（NYHA III or IV）
• HIV infection or AIDS
• subjects cannot be able to complete the assessment including dementia or other mental disorders, limited physical activity, severe visual impairment
• simple hematuria