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In mechanically ventilated patients during supine position, alveolar collapse usually distributes in dependent lung region.Decrease of flow trigger sensitivity might improve homogeneous of tidal volume distribution.
In mechanically ventilated patients during supine position, alveolar collapse usually distributes in dependent lung region. High positive end expiratory pressure (PEEP) has been applied to improve the homogeneous distribution of ventilation by increasing the end expiratory lung ventilation (EELV) and alveolar recruitment. However, for patients who increasing PEEP in some extent still existed poor aeration in the dependent region, further elevating PEEP seems to be unreasonable that perhaps lead to overdistension. Decreasing trigger sensitivity might further evoke inspiratory efforts to improve the ventilation for this type of patients.The Electrical impedance tomography (EIT) was applied in monitoring the regional ventilation distribution at the bedside.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| the lowest trigger sensitivity | The flow trigger of ventilator was set as the lowest level of sensitivity. |
| |
| the highest trigger sensitivity | The flow trigger of ventilator was set as the highest level of sensitivity. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| flow trigger | Procedure | The flow trigger will be adjust during the pressure assist ventilation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The homogeneity of distribution of tidal volume | EIT was used to monitoring the homogeneity of distribution of tidal volume that was divided into two contiguous regions of interest (ROI) equally, the dependent and non-dependent area. The ratio of relative distribution of tidal ventilation of two ROI was calculated. | within 20 minutes after changing flow trigger |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in global and regional EELV | The change of EELV was measured after changing flow trigger based on the baseline level. | within 20 minutes after changing flow trigger |
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Inclusion Criteria:
Exclusion Criteria:
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The postoperative patients receiving pressure support ventilation and existing heterogenous ventilation.
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| Name | Affiliation | Role |
|---|---|---|
| Jian-Xin Zhou, MD | Beijing Tiantan Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jian-Xin Zhou | Beijing | Beijing Municipality | 100050 | China |
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