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This study proposes to establish a CT radiomics-based prediction model for identifying metastasis lymph nodes in esophageal cancer.
This study proposes to establish an image feature extraction and selection method for identifying lymph node metastasis of esophageal cancer.The study will consider the relationship between the main lesion and the suspected lymph node, extract association characteristics in order to improve the sensitivity and specificity of the CT radiomics-based prediction model for identifying metastasis lymph nodes. The study includes the construction of CT radiomics-based prediction model and the validation of the prediction model.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| preoperative enhanced chest CT | The cohort contains patients with preoperative therapies and patients without preoperative therapies. Each patient receives regular preoperative enhanced chest CT; for patients with preoperative therapies, they usually undergo twice enhanced chest CT examination at before and after preoperative therapies, the CT images after preoperative therapies will be used for analysis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| preoperative enhanced chest CT examination | Procedure | Each patient will receive preoperative enhanced chest CT examination, and their CT images will be used for analysis |
|
| Measure | Description | Time Frame |
|---|---|---|
| pathological local lymph node status | pathological lymph node status is defined as lymph node metastasis exist or not | Pathologic evaluation will be performed for each patient within 1 week after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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pathologically proven esophageal cancer patients who receive preoperative CT and surgical resection in our hospital.
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| Name | Affiliation | Role |
|---|---|---|
| Ying-Shi Sun, MD | Dept.Radiology,Peking University Cancer Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing Cancer Hospital | Beijing | Beijing Municipality | 100142 | China |
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| ID | Term |
|---|---|
| D004938 | Esophageal Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| D006258 |
| Head and Neck Neoplasms |
| D004066 | Digestive System Diseases |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |