Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Identify, characterize and then validate electrophysiological markers linking electrophysiological cerebral activity and performance in cognitive and physical fatigability in humans. To do this, noninvasive explorations of electroencephalography (EEG) and magnetoencephalography (MEG) will be carried out under two conditions of different experiments, the first one that induces a cognitive fatigability and the second one that induces physical fatigability.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cognitive Fatigability | Other |
| |
| Physical Fatigability | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electroencephalography (EEG) multi-sensor | Other | Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG), which is a non-invasive method. |
| Measure | Description | Time Frame |
|---|---|---|
| Identify electrophysiological markers in humans depending on whether the experimental conditions induce cognitive fatigability. | The evaluation of cognitive performance will be carried out by means of conventional behavioral measures, of the press-button type, handling of a mouse or of a joystick and measurement of reaction time. | 7 hours |
| Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with EEG. | Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG). | 7 hours |
| Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with MEG. | Electrophysiological measurements of cerebral activity will be carried out by magnetoencephalography (MEG) | 7 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Refine (locate at the level of the cortex), the origin of these physiological markers | Several types of recordings, passive and non-invasive, will be realized:
| 7 hours |
Not provided
Inclusion Criteria MGPFco group:
Inclusion Criteria MGPFph group:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Julien JUNG, MD | Hospices Civils de Lyon | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospices Civils de Lyon, HFME | Bron | 69500 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41133559 | Result | Poinsard L, Berthomier C, Clemencon M, Brandewinder M, Essid S, Damon C, Rigaud F, Benichoux A, Maby E, Fornoni L, Bouchet P, Beers PV, Massot B, Revol P, Creveaux T, Collet C, Mattout J, Pialoux V, Billat V. EEG-Metabolic Coupling and Time Limit at V O2max During Constant-Load Exercise. J Funct Morphol Kinesiol. 2025 Sep 26;10(4):369. doi: 10.3390/jfmk10040369. | |
| Result | Véronique Billat, Christian Berthomier, Michel Clémençon, Marie Brandewinder, Slim Essid, Cécilia Damon, François Rigaud, Alexis Bénichoux, Emmanuel Maby, Lesly Fornoni, Patrick Bouchet , Pascal Van Beers, Bertrand Massot, Patrice Revol, Luc Poinsard, Thomas Creveaux, Christian Collet, Jérémie Mattout and Vincent Pialoux. Electroencephalography Response during an Incremental Test According to the VO2max Plateau Incidence. Applied Sciences. 2024, 14, 5411. | ||
| 38238759 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Magnetoencephalography (MEG) | Other | Electrophysiological measurements of brain activity will be performed by magnetoencephalography (MEG) which is a non-invasive method. |
|
| Behavioral Measures | Other | The evaluation of cognitive performance will be carried out by means of behavioral measures, push-button type, handling of a mouse or a joystick. |
|
| Reaction time measurement | Other | The assessment of cognitive performance will be carried out using standard behavioral measures, such as reaction time measurement. |
|
| Assessment of physical performance | Other | The assessment of physical performance will be based both on bioenergetic measurements and on quantitative data collected in continuous and relative to the effort (eg instantaneous pedaling speed). |
|
| Electrooculogram (EOG) | Other | In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study. |
|
| Electromyogram (EMG) | Other | In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study. |
|
| Electrocardiogram with 3 leads | Other | In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study. |
|
| Electrodermogram (EDG) | Other | In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study. |
|
| Consumption of O2 (VO2) | Other | In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study. |
|
| Production of CO2 (VCO2) | Other | In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study. |
|
| Distinguish between different time scales of performance |
Several types of recordings, passive and non-invasive, will be realized:
|
| 7 hours |
| Derived |
| Seguin P, Maby E, Fouillen M, Otman A, Luaute J, Giraux P, Morlet D, Mattout J. The challenge of controlling an auditory BCI in the case of severe motor disability. J Neuroeng Rehabil. 2024 Jan 18;21(1):9. doi: 10.1186/s12984-023-01289-3. |
| ID | Term |
|---|---|
| D015225 | Magnetoencephalography |
| D010101 | Oxygen Consumption |
| ID | Term |
|---|---|
| D003943 | Diagnostic Techniques, Neurological |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D004568 | Electrodiagnosis |
| D060306 | Magnetometry |
| D008919 | Investigative Techniques |
| D008660 | Metabolism |
Not provided
Not provided