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This study aims at evaluating the safety of an approach based on HLA-mismatched Microtransplantation without immunosuppressive treatment in patients With myeloid hemopathies who are ineligible to conventional allograft
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HLA-mismatched microtransplantation | Experimental | HLA-mismatched microtransplantation without immunosuppressive treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HLA-mismatched microtransplantation | Biological | 3 administrations of hematopoietic stem cells without immunosupression |
|
| Measure | Description | Time Frame |
|---|---|---|
| Occurrence of acute Graft versus Host disease after a HLA-mismatched transplantation without an immunosuppressive treatment | Cumulative incidence of acute GVH (grade 1 to 4) | 100 days after transplantation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut Paoli Calmettes | Marseille | Bouches du Rhône | 13009 | France |
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| ID | Term |
|---|---|
| D015470 | Leukemia, Myeloid, Acute |
| D009190 | Myelodysplastic Syndromes |
| ID | Term |
|---|---|
| D007951 | Leukemia, Myeloid |
| D007938 | Leukemia |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| D006402 |
| Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D001855 | Bone Marrow Diseases |