Hepatitis A is the most prevalent hepatitis which account for approximately 45% . The susceptible population is Children and adolescence, also the morbidity in adult presented rising trend in recent years. Therefore, vaccination of Hepatitis A Vaccine play an important role in National Immunisation Program(China). The aim of this experiment is to verify the effects of experimental group non-inferior than control group. The experiment methods is compared the difference of seroconversion rate and Antibody geometric mean titer (GMT)between experimental and control Hepatitis A Vaccines. In addition, evaluating the safety of two Hepatitis A Vaccines in 18-24 months Chinese Children.

Inclusion Criteria:

• The healthy children in mental and physical aged between 18-24 months, and the guardians agree and fully understand the protocol.
• No Hepatitis A disease and contraindication of vaccination
• No history of Hepatitis A Vaccine
• The subjects can follow the requirements of experiment project.
• Do not vaccinate other vaccine in one months.
• Axillary's temperature≤37℃

Exclusion Criteria:

• Having severe diseases.
• Allergy to the components in Vaccine
• Immune abnormalities
• The people who do not agree with the Inclusion Criteria
• Have a serious chronic disease
• Any conditions which researcher think will influence the results or the subjects.

Based on the literature public progress.