Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| CPP-SC 010/2013 | Other Identifier | Rouen University, Normandy France |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| ADIR Association | OTHER |
Not provided
Not provided
Not provided
Not provided
Chronic Obstructive Pulmonary Disease (COPD) patients are more likely to develop acute hypercapnic respiratory failure. In the acute phase, non invasive ventilation has been shown to improve mortality and reduce intubation rate. Few studies are available about long term benefits of home non invasive ventilation in COPD patients with chronic hypercapnic respiratory failure who survived after an acute episode. The purpose of this study is to determine whether home non invasive ventilation can reduce recurrent acute hypercapnic respiratory failure in COPD patients who survived an acute hypercapnic respiratory failure episode treated by non invasive ventilation.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Long Term Oxygen Therapy alone | No Intervention | Long Term oxygen therapy is prescribed according to the guidelines | |
| Non invasive ventilation | Active Comparator | Home non invasive ventilation is prescribed with the following settings
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Home ventilator | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| acute hypercapnic respiratory failure episode | first episode of acute hypercapnic respiratory failure episode requiring hospitalization | up to 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| acute hypercapnic respiratory failure episode rate | up to 24 months | |
| pulmonary function test | at one month and every six months up to 24 months | |
| Six Minute Walk Distance |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bouchra Lamia, MD, MPH, PhD | Contact | 0685426884 | 33 | bouchra.lamia@chu-rouen.fr |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CH Dieppe | Recruiting | Dieppe | France |
Not provided
| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D012131 | Respiratory Insufficiency |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| at one month and every six months up to 24 months |
| Quality of life | at one month and every six months up to 24 months |
| Heart function | left and right heart function assessed using echocardiography | at one month and every six months up to 24 months |
| Cost effectiveness | at one month and every six months up to 24 months |
| mortality | at one month and every six months up to 24 months |
| arterial blood gas | at one month and every six months up to 24 months |
| CH Elbeuf | Recruiting | Elbeuf | France |
|
| Le Havre, Jacques Monod Hospital | Recruiting | Montivilliers | 76290 | France |
|
| CHU de Rouen | Recruiting | Rouen | 76000 | France |
|
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012120 | Respiration Disorders |