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This is a prospective cohort study. The main objective is to compare the prevalence of a "full stomach" using gastric ultrasound technique, in elective surgical patients with diabetes mellitus compared to non-diabetic controls following the present fasting guidelines (2 h after clear liquid and 6h after a light meal). For patients with a full stomach or intermediate stomach, an consecutive ultrasound scan is performed every 10 min,until empty stomachstomach contents are detected to determine the mean gastric emptying time for clear liquid and light meal, and to investigate the risk factors for delayed stomach emptying in diabetic patients by logistic regression analysis .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diabetic patients |
| ||
| Non-diabetic patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fasting 2 h after clear liquid or 6h after a light meal | Other | The fasting time for all patients is 2 h after clear liquid or 6h after a light meal, then gastric ultrasound examination is performed. |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of full stomach | The frequency of a "full stomach" in the diabetic population compared to a non-diabetic control population at 2h after ingesting clear liquid or 6h after light meal. | one day |
| Measure | Description | Time Frame |
|---|---|---|
| Mean gastric emptying time of clear liquid and light meal | The mean gastric emptying time of clear liquid and light meal in both diabetic and non-diabetic population. | one day |
| Measure | Description | Time Frame |
|---|---|---|
| Risk factors of delayed stomach empty in diabetic patients | Correlation between the latest fast, postprandial plasma glucose concentration, hemoglobin A1c level and the diabetes complications ( peripheral neuropathy, cardiovascular autonomic neuropathy, diabetic nephropathy,and diabetes mellitus-related eye disease (including diabetic retinopathy, macular edema, rubeosis iridis, vitreous hemorrhage and diabetic related-visual injury)) with delayed stomach empty |
Inclusion Criteria:
Exclusion Criteria:
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Study participants will be diabetic and non-diabetic patients who are admitted to the surgical department and scheduled to undergo elective surgical procedures. 100 participants will be recruited in total.
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| Name | Affiliation | Role |
|---|---|---|
| Chunling Jiang | West China Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West China Hospital | Chengdu | Sichuan | 610041 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31601180 | Derived | Zhou L, Yang Y, Yang L, Cao W, Jing H, Xu Y, Jiang X, Xu D, Xiao Q, Jiang C, Bo L. Point-of-care ultrasound defines gastric content in elective surgical patients with type 2 diabetes mellitus: a prospective cohort study. BMC Anesthesiol. 2019 Oct 10;19(1):179. doi: 10.1186/s12871-019-0848-x. |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| one day |