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Analgesia following video-assisted thoracoscopic surgery (VATS) is important for the prevention of postoperative pulmonary complications.Various regional methods of anesthesia are currently being used to achieve this goal. The aim of the study was to assess the effectiveness of SAPB on postoperative VATS analgesia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group S | Experimental | IV patient-controlled analgesia (PCA) tramadol+Serratus Anterior Plane Block(SAPB) Tramadol infusion (PCA): 400 mg tramadol, IV 4 mg/mL tramadol solution into 100 mL normal saline; PCA settings: 0.3 mg/kg bolus, 10 mg Demand dose and 20 min lock out interval, six-hour limit infusion to attain 100 mg. Maximum daily dose was set at 400 mg. 20 mL of bupivacaine at a concentration of 0.25% to between serratus anterior and intercostal muscle using the in-line technique for SAPB. |
|
| Group T | Active Comparator | IV patient-controlled analgesia (PCA) tramadol Tramadol infusion (PCA): 400 mg tramadol, IV 4 mg/mL tramadol solution into 100 mL normal saline; PCA settings: 0.3 mg/kg bolus, 10 mg Demand dose and 20 min lock out interval, six-hour limit infusion to attain 100 mg. Maximum daily dose was set at 400 mg. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Serratus Anterior Plane Block | Procedure |
| ||
| IV patient-controlled analgesia (PCA) tramadol |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analogue Scale | Visual Analogue Scale was used for pain | Postoperative 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| tramadol consumption | tramadol consumption | Postoperative 24 hour |
| Ramsay sedation scale (RSS) | Ramsay sedation scale (RSS) | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| side effect profile | side effect profile | 24 hours |
| additional analgesic use | additional analgesic use | 24 hours |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Burcu Metin Ökmen | Bursa Yuksek Ihtisas Training and Research Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D016058 | Analgesia, Patient-Controlled |
| D010323 | Passive Cutaneous Anaphylaxis |
| D014147 | Tramadol |
| ID | Term |
|---|---|
| D000698 | Analgesia |
| D000760 | Anesthesia and Analgesia |
| D012882 | Skin Tests |
| D007159 | Immunologic Tests |
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Prospective, randomized, controlled, single-blind
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| Drug |
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| D019411 |
| Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D008919 | Investigative Techniques |
| D007158 | Immunologic Techniques |
| D000937 | Antigen-Antibody Reactions |
| D055633 | Immune System Phenomena |
| D003511 | Cyclohexanols |
| D000441 | Hexanols |
| D005233 | Fatty Alcohols |
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
| D004123 | Dimethylamines |
| D008744 | Methylamines |
| D000588 | Amines |
| D008055 | Lipids |