Comparison of 3 Methods to Diagnose Endolymphatic Hydrops in Meniere's Disease

Diagnostic Agreement of Electrophysiological Audiovestibular Examinations With Magnetic Resonance Imaging (MRI) of the Inner Ear in Revealing Endolymphatic Hydrops (EH) in Patients With Certain or Probable Meniere's Disease (MD)

The aim of this study is to compare 3 methods for the diagnosis of endolymphatic hydrops (EH) in patients with Meniere's disease: MRI 3 Tesla (to visualise EH directly), and functional explorations, namely electrocochleography and dephasing of acoustic distortion products (which are modified by the EH).

The research hypothesis is that the examinations will show agreement in the diagnosis of EH, and that the results obtained (quantitative values) will vary in the same direction over time and during flares of MD.

Inclusion Criteria:

• persons who have provided written consent
• persons aged 18 to 75 years
• persons with certain, probable or possible Meniere's disease according to the international classification AAO-HNS

Exclusion Criteria:

• persons without health insurance cover
• adults under guardianship
• persons with a history of hypersensitivity to the active substance or to one of the excipients of the contrast agent used for the MRI or to any gadolinium chelate
• pregnant or breast-feeding women
• severe acute or chronic kidney failure
• other identified causes of cochleo-vestibular syndromes
• Impossibility to follow-up or carry out any of the examinations necessary for the protocol