Effect of Treatment of Low Anterior Resection Syndrome After Rectal Cancer Surgery

A Randomized Controlled Study of the Effect of Treatment of Low Anterior Resection Syndrome (LARS) After Rectal Cancer Surgery

A randomized controlled trial (RCT) in patients who underwent sphincter preserving surgery due to rectal cancer. The study will analyze the effect of Transanal irrigation (TAI) and medication that can help control of the bowel movement in patients with low anterior resection syndrome.

A randomized controlled trial (RCT) in patients who underwent sphincter preserving surgery due to rectal cancer.

The study will analyze the effect of Transanal irrigation (TAI) and medication that can help control of the bowel movement in patients with low anterior resection syndrome.

An interim analysis will be made after 40 included patients in the study.

Inclusion Criteria:

• Patients that have undergone surgery for rectal cancer (sphincter saving surgery, low anterior resection)
• Adult ≥ 18 years old
• Have scoring major LARS (according to the Low anterior resection syndrome score)

Exclusion Criteria:

• stoma
• recurrent disease
• Another colorectal surgery
• Inflammatory bowel disease (IBD)