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Characterization of the female genital tract microbiome in women undergoing IVF treatment
The primary goal With The purpose of our study is to examine the uterine microbiome by Next-generation sequencing of the bacteria specific regions .
Vaginal and uterine swabs will be taken in different women undergoing IVF /PGD. Novel bacteria and results of taxonomy assignments will be examine to find correlation of uterine flora with IVF and obstetrical outcomes.
The metagenomics approach will be used to seek previously unidentified bacterial species in the human upper genital tract.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endometrial sampling of a Typical Embryo transfer catheter | Diagnostic Test | no intervention no additional change from unit protocol |
|
| Measure | Description | Time Frame |
|---|---|---|
| To assess endometrial caracteristicas in fertile and infertile women using next generation sequencing of bacterial identification | Type of flora identified by next generation sequencing of bacterial identification | 2017-2020 |
| To identify specific endometrial flora in association to faliure of IVF treatment | Type of flora identified by NGS | 2017-2020 |
| to assess the feasibility of endometrial sampling in women undergoing embryo transfer by a standart transfer cateteher | Mode of endometrial sampling | 2017-2020 |
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Inclusion Criteria:
Exclusion Criteria:
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All infertile women
patients undergoing transfer of a single euploid blastocyst .The specimen will be obtaine from the embryo transfer catheter.
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Bacterial DNA only