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| Name | Class |
|---|---|
| NeuroCure Clinical Research Center, Charite, Berlin | OTHER |
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The purpose of the study is to systematically capture and characterize mental comorbidities for patients with myasthenia gravis. Anxiety disorders and depression for example, can negatively affect the quality of life and lead to e.g. unemployment and early retirement especially in young patients.
Additionally the researchers want to find out in what way certain aspects of the disease have an influence on the quality of life, and whether different concepts of coping with the disease have different effects on the quality of life for patients with myasthenia gravis.
During the study, close relatives of patients will also be asked to provide input about their current stress situation in the context of supporting their relative.
Based on the results, the investigators want to improve and supplement established treatment concepts, to ensure a more comprehensive and individual treatment.
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| Measure | Description | Time Frame |
|---|---|---|
| Questionnaire Survey (Patient) |
| directly after inclusion in the study |
| Measure | Description | Time Frame |
|---|---|---|
| "Häusliche Pflegeskala" (HPS) | questionnaire is used to assess social work Intervention and couple's counselling | directly after inclusion in the study |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with Myasthenia Gravis and their relatives
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| Name | Affiliation | Role |
|---|---|---|
| Andreas Meisel, Prof. Dr. med. | Charite University, Berlin, Germany | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NeuroCure Clinical Research Center (NCRC), Charité | Berlin | 10117 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36369246 | Result | Marbin D, Piper SK, Lehnerer S, Harms U, Meisel A. Mental health in myasthenia gravis patients and its impact on caregiver burden. Sci Rep. 2022 Nov 11;12(1):19275. doi: 10.1038/s41598-022-22078-3. |
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| ID | Term |
|---|---|
| D009157 | Myasthenia Gravis |
| D003863 | Depression |
| D001008 | Anxiety Disorders |
| D013313 | Stress Disorders, Post-Traumatic |
| ID | Term |
|---|---|
| D020361 | Paraneoplastic Syndromes, Nervous System |
| D009423 | Nervous System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| D010257 | Paraneoplastic Syndromes |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D019636 | Neurodegenerative Diseases |
| D020511 | Neuromuscular Junction Diseases |
| D009468 | Neuromuscular Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D001523 | Mental Disorders |
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |