Functional Evaluation of Two Infant Formula Supplemented With Probiotics Isolated From Breast Milk

Functional Evaluation of Two Infant Formula Supplemented With Probiotics Isolated From Breast Milk

A randomized double blinded controlled study including infants at the age of 1 month . Infants are assigned randomly to either infant formula supplemented with B. breve CECT7263 or L.fermentum CECT5716 (Probiotic groups), or the same formula without the probiotic strain (Control group). The primary outcome of the study is the body weight gain of infants. Secondary outcomes are incidence of infections, symptoms related with intestinal function, and fecal microbiota

Inclusion Criteria:

• Newborn infants at term (37-42 weeks gestational age) healthy during the first month of life, for reasons unrelated to the study, abandon breastfeeding during the first month of life.
• Signature of informed parental or guardian consent.

Exclusion Criteria:

• Allergic to the protein in cow's milk.
• Lactose intolerant.
• Suffering from a serious metabolic disease.
• They have experienced or are experiencing some severe gastrointestinal disease.
• Receive some form of chronic medication or are receiving antibiotics at the time of capture.
• Low expectation of compliance with the study protocol.
• allergic to any group of antibiotics.