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The collected data from the Zurich Registry for pulmonary Hypertension (PH) are evaluated in a retrospective analysis. This study examines the number of patients and their exact diagnoses who are treated at the University Hospital of Zurich and potentially other participating in the Zurich Registry. Other demographic parameters such as age, gender and body-mass-index are also part of the evaluation. Furthermore, the analysis will focus on the newest guidelines on PH. Therefore, it will be checked how many patients would fulfill the therapeutic goals in terms of New York Heart Classification (NYHA), 6-minute walk distance, sign of right heart failure and N-terminal pro-brain-natriuretic peptide(NTproBNP). Additionally, the study examines on how the patients are treated. Despite the different kind of Drugs, the focus lies on the combination therapy (single, double, triple) and the impact the therapy had on the patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pulmonary arterial hypertension | |||
| Chronic thromboembolic pulmonary hypertension |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in NYHA/WHO functional class | Change of the functional class over time in relation to given vasodilator treatment | Baseline, 3 months, 6 months, 1 year |
| Change in 6 minute walk distance | Change of the 6 minute walk distance over time in relation to given vasodilator treatment | Baseline, 3 months, 6 months, 1 year |
| Change in NT-proBNP | Change of the 6 minute walk distance over time in relation to given vasodilator treatment | Baseline, 3 months, 6 months, 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients that are in NYHA/WHO functional class <= II | Percentage of patients that are in NYHA/WHO functional class <= II will be assessed at respective timepoints | Baseline, 3 months, 6 months, 1 year |
| Percentage of patients with a 6 minute walk distance > 440m |
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Inclusion Criteria:
Exclusion Criteria:
-
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PAH and CTEPH patients diagnosed with a right heart catheter
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Respiratory Clinic, University Hospital of Zurich | Zurich | 8091 | Switzerland |
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| ID | Term |
|---|---|
| D006976 | Hypertension, Pulmonary |
| D065627 | Familial Primary Pulmonary Hypertension |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D006973 | Hypertension |
| D014652 | Vascular Diseases |
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Percentage of patients with a 6 minute walk distance > 440m will be assessed at respective timepoints |
| Baseline, 3 months, 6 months, 1 year |
| Percentage of patients with a NT-proBNP < 300 ng/l | Percentage of patients with a NT-proBNP < 300 ng/l will be assessed at respective timepoints | Baseline, 3 months, 6 months, 1 year |
| D002318 |
| Cardiovascular Diseases |