A Study to Assess the Pharmacodynamics (PD) of Prednisoline in Healthy Male Subject

An Experimental Medicine Study to Assess the Pharmacodynamics Following Administration of Multiple Doses of Prednisolone to Healthy Male Subjects

The purpose of this study is to assess the pharmacodynamics of Prednisolone in healthy male subjects

Inclusion Criteria:

• Healthy male subjects as determined by no clinically significant deviation from normal in medical history, physical examination, ECGs, and clinical laboratory determinations
• Body Mass Index (BMI) of 18 to 30 kilogram / square meter (kg/m2), inclusive
• Signed informed consent

Exclusion Criteria:

• Women
• Any significant acute or chronic medical illness
• Current or recent (within 3 months) gastrointestinal disease including peptic ulcer

Other protocol inclusion/exclusion criteria may apply