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Determine the short-term and lasting effects of intensity-matched exercise programs on level 2-3 PD patients' clinical symptoms, postural control, and mobility.
Hypothesis
Agility: Xbox based high intensity program, as detailed in the submitted manuscript. Borg scale after after each exercise block is recorded. Heart rate continuosly measured. These data are used to set intensity in the fitness group.
Fitness: A stationary bicycle ergometer program that includes visual stimulation in the form of watching nature programs and movies to account for visual stimulus in Agility group. Mean heart rate and Borg scale readings from Agility group will form the target intensity.
Control: No-exercise, measurment-only control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High intensity agility group | Experimental | Exercise therapy |
|
| Non-agility cycling group | Experimental | Parkinson's Bicycle Group, which takes 1 hour of exercise every day for 5 weeks |
|
| No-exercise control group | No Intervention | Control Parkinson's disease control group thad will not receive exercise treatment |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Single-blind RTC of PD patients | Other | The groups participate in observation for 5 weeks. Two groups take part in a motion therapy over the 5-week period. |
|
| Measure | Description | Time Frame |
|---|---|---|
| EQ5D-5L | Questionnaire | 0-5 scale (5 weeks-long, the higher score is better) |
| Borg test | Fatigue questionnaire | 0-40 point (5 week-long, higher score is better) |
| PDQ-39 | special Parkinson's Disease test - motor and no-motor function | 0-39 scale (5week-long, higher score is better) |
| SPPB test (gait, balance, leg stregth) | Walking and balance testing | 0-12 scale (5 week-long, higher score is better) |
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Inclusion Criteria:
Exclusion Criteria:
• Severe heart problems, severe demeanor, alcoholism, drug problems,
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Somogy Megyei Kaposi Mór Teaching Hospital | Kaposvár | Somogy County | 7400 | Hungary |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38588457 | Derived | Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3. | |
| 36602886 |
| Label | URL |
|---|---|
| Description Related Info | View source |
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| cycling | Other | Patients must undergo a daily exercise cycle of 1 hour during the intervention |
|
| Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2. |
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
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