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| ID | Type | Description | Link |
|---|---|---|---|
| ID-RCB | Other Identifier | 2017-A01180-53 |
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| Name | Class |
|---|---|
| University Hospital of Saint-Etienne | OTHER |
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Crying is the primary signaling strategy available to the human newborn for eliciting parental care. Yet, the investigators only have superficial understanding of the information carried by cries, and how this information is perceived by parents. Using modern tools of sound processing and functional Magnetic Resonance Imaging (fMRI) experiment, this study aims to investigate cry-induced brain activation in adult depending on the cry's acoustic properties expressing various degrees of stress and distress levels. For that, Adults will be tested inside a fMRI magnet to determine their brain activations elicited by different babies cries according to whether the cry was evoked in a pain situation or not. The cerebral activity will be investigated in relation to acoustic features of cries (e.g. with pitch and/or roughness variations). To test if the gender or parentally of adult listeners influence their perceptions and brain responses, the task will be applied to 2 different groups (men and women not-parents). The hypothesis is that the brain of adult listeners will be able to discriminate adequately the intensity of the pain mediated by the cries. This process should involve brain areas such as the insular and the orbito frontal cortex that are known to participate in the integration of pain intensity and pain controls. The experiment should also determine which one of the acoustic features is able to transmit pain and to recruit brain areas involved in pain processes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Men contact-less with children | Experimental | functional Magnetic Resonance Imaging (fMRI). |
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| Women contact-less with children | Experimental | functional Magnetic Resonance Imaging (fMRI). |
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| Father contact-less with children | Experimental | functional Magnetic Resonance Imaging (fMRI). |
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| Mother contact-less with children | Experimental | functional Magnetic Resonance Imaging (fMRI). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| functional Magnetic Resonance Imaging (fMRI) | Other | During fMRI, healthy volunteers will listen 80 baby's cry. |
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| Measure | Description | Time Frame |
|---|---|---|
| BOLD (blood-oxygen-level dependent) -contrast imaging | Measure of blood-oxygen-level dependent with fMRI during listening to natural crying. | at inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| BOLD (blood-oxygen-level dependent) -contrast imaging | Measure of blood-oxygen-level dependent with by fMRI during listening to artificial crying. | at inclusion |
| impact of gender and parenting on perception of baby's cry |
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Inclusion Criteria:
Exclusion Criteria:
40 women and 40 men
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| Name | Affiliation | Role |
|---|---|---|
| Roland PEYRON, MD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Neurologie - CHU de Saint-Etienne | Saint-Etienne | 42055 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41557145 | Derived | Fauchon C, Corvin S, Faillenot I, Patural H, Reby D, Peyron R, Mathevon N. Parenting and empathy capabilities drive brain response to pain cues in baby cries. Pain. 2026 May 1;167(5):1225-1236. doi: 10.1097/j.pain.0000000000003914. Epub 2026 Jan 15. |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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20 men and 20 women : group "non parent" 20 father and 20 mother : group "parent"
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Measure of blood-oxygen-level dependent with by fMRI during listening to artificial crying.
| at inclusion |