The study will assess vaginal microbiota levels before and after antibiotic treatment in females infected with Bacterial Vaginosis (BV).

This method validation study will endeavour to obtain evidence for:

• Recruitment methodology effectiveness
• The usefulness of the "Canestest" test as a screening tool
• The time required for the vaginal microbiota (particularly Lactobacillus count) to return to normal after treatment of BV infection with metronidazole.
• The time required for the Nugent Score to return to normal after treatment of BV infection with metronidazole.

Inclusion Criteria:

• Signed informed consent
• Female gender
• Over 18 years of age
• Have a high probability for compliance with and completion of the study

Exclusion Criteria:

• Hypersensitivity to metronidazole --only applies to Group 2.
• Post-menopausal defined as at least 12 consecutive months without menstruation
• Treatment of BV in last 4 weeks
• Clinically significant menstrual irregularities
• Suspected presence of STDs or other vaginal infection
• Pregnancy
• Breast feeding
• Participation in other clinical studies which could influence genitourinary tract microbiota
• Substance abuse
• Investigator believes that the participant may be uncooperative and/or noncompliant and should therefore not participate in the study

No plan to share IPD