Noninvasive Positive Pressure Ventilation in Overlap Syndrome

The Effectiveness of Noninvasive Positive Pressure Ventilation Treatment in Overlap Syndrome

Chronic obstructive pulmonary diseases (COPD) coexisting with obstructive sleep apnea is called overlap syndrome (OS). Patients with OS seem to have worse prognosis than patients with only one disorder. Noninvasive positive pressure ventilation is an efficient treatment in obstructive sleep apnea, but the effectiveness in improving outcomes of OS patients is still not fully investigated. The aim of this non-randomized concurrent control trial is to evaluate noninvasive positive pressure ventilation's effectiveness in OS patients.

Inclusion Criteria:

• patients with COPD and sleep apnea dyspnea syndrome

Exclusion Criteria:

• patients with non-stable hemodynamics;
• patients with limited life expectancy;
• patients with other severe respiratory diseases;
• patients with motor neuron diseases;
• patients with contraindications for NIPPV