Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to determine the efficacy and safety of DWP14012 compared to esomeprazole in the treatment of erosive gastroesophageal reflux disease classified as Los Angeles(LA) classification grades A to D.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DWP14012 20mg | Experimental | DWP14012 20mg, tablet, orally, once daily |
|
| DWP14012 40mg | Experimental | DWP14012 40mg, tablet, orally, once daily |
|
| DWP14012 80mg | Experimental | DWP14012 40mg*2, tablet, orally, once daily |
|
| Esomerpazole 40mg | Active Comparator | Esomerpazole 40mg, tablet, orally, once daily |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DWP14012 | Drug | tablet |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Ratio of subjects who were completely cured of mucosal defects by 8 weeks | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Ratio of subjects who were completely cured of mucosal defects by 4 weeks | 4 weeks |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hanyang University Medical Center | Sungdong-gu | Seoul | 04763 | South Korea |
Not provided
Not provided
Not provided
Not provided
Not provided
| Esomeprazole |
| Drug |
tablet |
|
|
| DWP14012 placebo | Drug | tablet |
|
| Esomeprazole placebo | Drug | tablet |
|
| ID | Term |
|---|---|
| C000634065 | fexuprazan |
| D064098 | Esomeprazole |
| ID | Term |
|---|---|
| D009853 | Omeprazole |
| D053799 | 2-Pyridinylmethylsulfinylbenzimidazoles |
| D013454 | Sulfoxides |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D001562 | Benzimidazoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
Not provided
Not provided