IRM Cognition in Patients With Head Trauma

Longitudinal Descriptive Study of the Correlation Between Cognitive Functions, White Matter Anatomical Pathways and Functional Magnetic Resonance Imaging Activations in Patients With Moderate to Severe Head Trauma.

Longitudinal descriptive study of a cohort of twenty brain-damaged patients for a two years period.

The following data are collected in 3 months, 12 months then 24 months after the accident with followed data collection :

• Clinical, neuropsychological assessments
• Diffusion magnetic resonance imaging (MRI) for the reconstruction of anatomical pathways
• Functional imaging data.

Inclusion Criteria:

• Adult patients, over the age of 18.
• Mild traumatic brain injury (Initial Glasgow score between 9 and 12)
• Severe brain injury (Initial Glasgow score between 3 and 8),
• Diffuse axonal injury and/or focal lesions.

Exclusion Criteria:

• Patients with MRI contraindications,
• Antecedents of brain lesions,
• Important lesions of the lobes and cortex on cerebral CT,
• Anoxic lesions related to cardiorespiratory arrest,
• Must be able to perform neuropsychological tests,
• Visual and auditory impairments.
• Aphasia