The Study of Efficacy and Safety of 2% Ketoconazole Cream in Thai Females With Mild Degree of Post - Adolescence Acne

The Study of Efficacy and Safety of 2% Ketoconazole Cream in Thai Females With Mild Degree of Post - Adolescence Acne

To study efficacy (total numbers of acne reduction) and safety of 2% Ketoconazole cream in Thai females with Mild degree Post-Adolescence acne comparing with placebo for a period of 12 weeks.

Inclusion Criteria:

• regular menstrual cycle with mild degree of post - adolescence acne
• agree to stop topical and systemic medication for acne treatment for 2 and 4 weeks respectively.

Exclusion Criteria:

• Pregnancy or lactation
• Other active rashes on faces.
• Allergic to ketoconazole or other ingredients of preparation.
• Signs of hyperandrogenism
• Taking anti-androgenic medications.