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This study aims to find a correlation between cytokines levels and malignancy potential of different cystic types.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with pancreatic cysts | Active Comparator | Fine-needle aspiration (FNA) by Endoscopic Ultrasound (EUS) will collect liquid from patients' pancreatic cysts to measure their Interleukin and TNF levels |
|
| Healthy volunteers | Active Comparator | Laboratory blood test to measure Interleukin and TNF levels |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EUS with fine-needle aspiration of pancreatic cyst | Procedure | EUS with fine-needle aspiration |
|
| Measure | Description | Time Frame |
|---|---|---|
| Prediction of malignant potential of pancreatic cyst by measuring Interleukin levels | Interleukin 1,8,10 will be measured quantitatively by an enzyme-linked immunosorbent assay. The same interleukins levels will be measured in serum of same patients and control group. Results will enable classification of cysts to either high or low risk malignancy potential. | Two years |
| Prediction of malignant potential of pancreatic cyst by measuring TNF levels | TNF levels will be measured quantitatively by an enzyme-linked immunosorbent assay. The same TNF levels will be measured in serum of same patients and control group. Results will enable classification of cysts to either high or low risk malignancy potential. | Two years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yael Kopelman, MD | Contact | 972-50-6246840 | yaelk@hy.health.gov.il |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hillel Yaffe Medical | Hadera | 38100 | Israel |
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One arm containing patients with pancreatic lesion and one control group arm of healthy volunteers
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| Laboratory Blood test | Diagnostic Test | Laboratory Blood Test |
|
| ID | Term |
|---|---|
| D010190 | Pancreatic Neoplasms |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
| D004066 | Digestive System Diseases |
| D010182 | Pancreatic Diseases |
| D004700 | Endocrine System Diseases |
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