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The investigators aim to determine the optimal number of measurements required for multiple-breath-washout derived lung function parameters in adults with pulmonary disease as well as in healthy controls
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| healthy controls |
|
| |
| chronic obstructive pulmonary disease |
|
| |
| bronchial asthma |
|
| |
| sarcoidosis |
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| multiple breath washout | Diagnostic Test | determination of lung clearance index using SF6 multiple breath washout |
|
| Measure | Description | Time Frame |
|---|---|---|
| change of lung clearance index (LCI) as determined by multiple breath washout | comparing the repeatability of duplicate vs. triplicate LCI measurements | 60 minutes |
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Inclusion criteria:
- informed consent
Exclusion Criteria:
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inpatients, outpatients, students, employees
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29228942 | Derived | Trinkmann F, Gotzmann J, Saur D, Schroeter M, Roth K, Stach K, Borggrefe M, Saur J, Akin I, Michels JD. Multiple breath washout testing in adults with pulmonary disease and healthy controls - can fewer measurements eventually be more? BMC Pulm Med. 2017 Dec 11;17(1):185. doi: 10.1186/s12890-017-0543-y. |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D001249 | Asthma |
| D012507 | Sarcoidosis |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001982 | Bronchial Diseases |
| D012130 | Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D006968 | Hypersensitivity, Delayed |