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Staffing changes at site. No longer feasible at site.
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The study evaluates the efficacy of two different anesthetic techniques in patients undergoing unilateral knee arthroscopy. Participants will be randomized to receive either subarachnoid block with 2-chloroprocaine or general anesthesia plus intravenous fentanyl.
The study evaluates the efficacy of two different anesthetic techniques in patients undergoing unilateral knee arthroscopy. Participants will be randomized to receive either subarachnoid block with 2-chloroprocaine or general anesthesia plus intravenous fentanyl. The study evaluates pain scores, opioid utilization and patient satisfaction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subarachnoid block | Experimental |
| |
| General anesthesia | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| General anesthesia | Procedure | General anesthesia will be delivered per standard procedure. General anesthesia will include induction with propofol 1-3mg/kg followed by placement of a laryngeal mask airway with maintenance anesthesia of sevoflurane 0.5-1 minimum alveolar concentration (MAC). |
| Measure | Description | Time Frame |
|---|---|---|
| Pain score | Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable. | Discharge from post anesthesia care unit (PACU) (usually one hour) |
| Pain score | Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable. | Post operative day one |
| Pain score | Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable. | One month postoperatively |
| Pain score | Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable. | Three months postoperatively |
| Opioid utilization | Opioid utilization based on amount of opioid medications administered | Surgical completion to PACU discharge (usually one hour) |
| Opioid utilization | Opioid utilization based on number of pain pills taken | Postoperative day one |
| Opioid utilization | Opioid utilization based on average number of pain pills taken per day | One month postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Patient satisfaction with anesthetic | Patient satisfaction with anesthetic based on 10-item patient satisfaction survey validated for regional and general anesthesia | 24 hours after PACU discharge |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jenna Walters, M.D. | Vanderbilt University Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | United States |
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| Subarachnoid block | Procedure | Neuraxial anesthesia will be performed at the L2-3 or L3-4 interspace with a 25-gauge Whitacre needle in the sitting position. After free flow of cerebrospinal fluid (CSF), 40-45mg of 2-chloroprocaine will be injected based on patient's height and discretion of attending anesthesiologist, needle withdrawn and the patient placed supine. |
|
| Opioid utilization | Opioid utilization based on average number of pain pills taken per day | Three months postoperatively |
| ID | Term |
|---|---|
| D000768 | Anesthesia, General |
| D000775 | Anesthesia, Spinal |
| ID | Term |
|---|---|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
| D000765 | Anesthesia, Conduction |
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