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Rectal cancer is one of the frequent malignant neoplasms ,Total mesorectal excision (TME) has become the gold standard treatment for middle and lower rectal cancers. Laparoscopic TME still be difficult in patients with low rectal tumors, narrow pelvic anatomy, male sex or high body mass index . Difficult visualization of the pelvic anatomy along with the limitation of rigid laparoscopic instruments may affect the quality of oncological outcomes and increase the risks of injuries during surgery. A down to up approach via transanal total mesorectal excision (TaTME) technique may overcome these problems
This clinical trial will be conducted at general surgery department of Assiut University Hospital .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| transanal TME | Experimental | Laparoscopic Assisted Transanal Total Mesorectal Excision |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laparoscopic Assisted Transanal Total Mesorectal Excision | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| intraoperative complication | complication occured intraoperatively or on the first day of surgery | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| resection margin | circumferential resection margin microscopic examination | 1 years |
| Mortality rate | rate of death | 1 years |
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Inclusion Criteria:
• rectal cancer histologically proven through biopsy
Exclusion Criteria:
• T4 tumours not responding to neoadjuvant chemo- radiotherapy
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| mohamed abulfetouh, MD | Contact | 0201098904323 | m.abulfetouh@aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| samir a ali, phd | assuit university hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assuit Universty Hospital | Asyut | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26310534 | Background | Kang L, Chen WH, Luo SL, Luo YX, Liu ZH, Huang MJ, Wang JP. Transanal total mesorectal excision for rectal cancer: a preliminary report. Surg Endosc. 2016 Jun;30(6):2552-62. doi: 10.1007/s00464-015-4521-2. Epub 2015 Aug 27. |
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| ID | Term |
|---|---|
| D012004 | Rectal Neoplasms |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
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|
| morbidity rate | rate of postoperative morbidity | 1 year |
| recurrance rate | rate of local recurance( by CT scan ) | 2 years |
| Anorectal function outcomes | manometric assessment of anorectal function | 2 years |
| Sexual functional outcomes | sexual function with IIEF(International Index of Erectile Function) questionnaire | 2 years |
| Mesorectal completeness | The quality of the mesorectum or TME specimen(pathological examination) | 1 year |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |