Clinical Application of Personal Designed 3D Printing Implants in Bone Defect Restoration

Shenzhen Hospital of Southern Medical University

Objective: Clinical application of 3D printing implant in bone defect treatment.

Study design: multicenter randomized controlled study . Methods:patients randomly grouped according to register number into internal fixation and bone graft group and 3D printing group. Reconstruct 3D models ,evaluate models preoperatively , simulate surgery in computer,design 3D implant, and 3D print implants,perform surgery with 3D implants to achieve the greatest degree of physiological reconstruction.Evaluate surgical efficacy .

Inclusion Criteria:

• Open fracture with bone defect
• Burst fracture of spine with bone defect
• Bone tumor with bone defect
• Bone tuberculosis with bone defect
• Nonunion with bone defect

Exclusion Criteria:

• Patients who can not tolerate anesthesia and surgery due to severe impairment of heart and lung function
• Systemic or local infection