Although the Magnetic resonance imaging with contrast is the gold standard for diagnosis of intra axial brain masses. The conventional Magnetic resonance imaging appearances of intra axial brain masses can be non-specific and even the use of contrast agent is of limited benefit.

Contrast enhancement reflects only disruption of blood brain barrier. One third of high-grade malignancies are non-enhanced and may non-neoplastic lesions show contrast enhancement.

Reliable differentiation of neoplastic from non-neoplastic brain masses, or of high grade from low grade tumor, is difficult with conventional Magnetic resonance imaging

1. Inclusion criteria:

   * An intra axial space occupying lesion/lesions detected on conventional structural imaging

2. Exclusion criteria:

   • MRI contraindications (as pace maker or claustrophobia).
   • Contrast hypersensitivity
   • Impaired renal function.
   • Pediatric age group

All Magnetic resonance imaging detected brain cases referred from Neurosurgery & Neuropsychiatry departments as well as Outpatient clinics