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This study seeks to determine the efficacy of single coil defibrillation leads for cardioversion of persistent atrial fibrillation.
This study seeks to compare the efficacy of single coil defibrillation leads for the internal cardioversion of atrial fibrillation as compared with cardioversion by external defibrillation pads. It is known that dual coil leads are effective for atrial cardioversion, but the presence of the SVC defibrillation coil allows for selection of shock vector that more reliably incorporates the majority of atrial tissue compared to a single right ventricular lead. For a variety of reasons single coil defibrillation leads are now implanted in the majority of patients requiring placement of implantable cardiac defibrillators, and many of these patient's will later develop atrial fibrillation and potentially require cardioversion. Currently, there is no clear consensus on how to approach cardioversion in these patient's and both external and internal methods are used. Internal cardioversion may be ineffective exposing patient's unnecessarily to repeated shocks and battery depletion. External cardioversion may carry a small risk of damaged to the CIED.
The investigator's goal is to identify patient's referred for cardioversion for atrial fibrillation who also have an implanted cardiac defibrillator with a single coil defibrillation lead and randomize them to either external or internal cardioversion.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Internal Cardioversion | Experimental | Patients randomized to external cardioversion will undergo external synchronized cardioversion per institutional protocol. |
|
| External Cardioversion | Active Comparator | Patients randomized to internal cardioversion will have a maximum energy shock delivered from the device between the RV coil and can. If cardioversion is not successful they will then undergo external cardioversion per institutional protocol. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Internal Cardioversion | Procedure | Internal Cardioversion with device maximum output shock from RV coil to Can versus external cardioversion per institutional protocol |
|
| Measure | Description | Time Frame |
|---|---|---|
| Acute Conversion of Atrial Fibrillation to Sinus Rhythm | Does the patient return for at least one beat to sinus rhythm following the administration of a shock | Immediate |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Samy C Elayi, MD | University of Kentucky | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Kentucky | Lexington | Kentucky | 40506 | United States |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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Participants will be randomized in block fashion to either internal or external cardioversion
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| External Cardioversion | Procedure | External Cardioversion per institutional protocol |
|
| D013568 |
| Pathological Conditions, Signs and Symptoms |