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| Name | Class |
|---|---|
| INSERM 1061, " Neuropsychiatry: epidemiological and clinical research", Montpellier | UNKNOWN |
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Eating disorders are multifactorial disorders currently conceptualized in a biopsychosocial model, but pathophysiology remains relatively unknown, and robust etiological models to guide treatment are therefore lacking. Different endophenotypes and neurocognitive vulnerability factors have been found in eating disorders including decision making abnormalities. The investigators hypothesize that decision making abnormalities are associated with a lower level of functioning and quality of life which could lead to social and interpersonal difficulties. The investigators also hypothesize that these anomalies are associated with a particular clinical profile (more restrictive profile, more hyperactivity, less insight on the disease and desire for care ...).
The investigators will recruit a total of 340 patients with an eating disorder in the university hospital of Montpellier.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants | Other | All participants performed the same evaluation: clinical and neuropsychological assessment. All of them are patients with an eating disorder. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ambulatory cares in a day-hospital (University Hospital of Montpellier) specialized in the evaluation of eating disorders | Behavioral | All patients assessed in the day-hospital will performed the same evaluation :
With the patient agreement, a biological collection will be constituted. The objective is the subsequent study of biological factors involved in eating disorders (in particular genetic factors) |
| Measure | Description | Time Frame |
|---|---|---|
| Level of functional impairment assessed by the Work and Social Adjustment Scale (WSAS) | We aim to investigate the link between decision-making and daily functioning of patients with eating disorder. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life assessed by the Eating disorder quality of life (EDQOL) scale. | We aim to investigate the link between quality of life and alteration of cognitive flexibility of patients with eating disorder. | Baseline |
| Level of functional impairment assessed by the clinician with the Functional Assessment Staging Test (FAST) scale |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Lapeyronie | Montpellier | 34295 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41987227 | Derived | Flaudias V, Gonthier C, Cornil A, Seneque M, Lakritz C, Iceta S, Guillaume S. Toward a triadic approach in eating disorders: investigating the contribution of the reflexive, affective and interoceptive systems in a clinical data cohort. J Eat Disord. 2026 Apr 15;14(1):134. doi: 10.1186/s40337-026-01602-0. |
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|
We aim to investigate the link between global functioning and alteration of cognitive flexibility of patients with eating disorder. |
| Baseline |
| Quality of life assessed by the Eating disorder quality of life (EDQOL) scale. | We aim to investigate the link between quality of life and alteration central coherence of patients with eating disorder. | Baseline |
| Level of functional impairment assessed by the clinician with the FAST scale | We aim to investigate the link between global functioning and alteration central coherence of patients with eating disorder. | Baseline |
| Score to decision making test (Iowa gambling task) | We aim to investigate the prognostic value of decision making abnormalities on the rates of recovery | At 12 months if patient is included in the ancillary study |
| Score to decision making test (Iowa gambling task) | We aim to investigate the prognostic value of decision making abnormalities on weight recovery (for anorexic patients) | At 12 months if patient is included in the ancillary study |
| Score to decision making test (Iowa gambling task) | We aim to investigate the prognostic value of decision making abnormalities on daily functioning | At 12 months if patient is included in the ancillary study |
| Score to decision making test (Iowa gambling task) | We aim to investigate the prognostic value of decision making abnormalities on switch to another subtype of eating disorder | At 12 months if patient is included in the ancillary study |
| Score to decision making test (Iowa gambling task) | We aim to investigate the impact of weight recovery on decision making abilities | At 12 months if patient is included in the ancillary study |
| ID | Term |
|---|---|
| D001068 | Feeding and Eating Disorders |
| D000856 | Anorexia Nervosa |
| D002032 | Bulimia |
| D056912 | Binge-Eating Disorder |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001523 | Mental Disorders |
| D006963 | Hyperphagia |
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