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Laparoscopic surgery is now widely established.Laparoscopic surgery involves insufflation of a gas (usually carbon dioxide) into the peritoneal cavity producing a pneumoperitoneum. The raised intra-abdominal pressure of the pneumoperitoneum, alteration in the patient's position and effects of carbon dioxide absorption cause changes in physiology, especially within the cardiovascular and respiratory systems.
The study will be carried out after approval of the ethical committee of Faculty of Medicine, Assiut University. A full preoperative anesthetic assessment will be carried out. Particular attention to the cardiovascular and respiratory systems is essential because of potential effects of the pneumoperitoneum and patient position.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laparoscopic Surgery | Procedure | Insufflation of a gas (carbon dioxide) into the peritoneal cavity producing a pneumoperitoneum will be done. The positioning of the patients in Trendelenburg position will be done. intraoperative and postoperative outcomes will be assesed |
| Measure | Description | Time Frame |
|---|---|---|
| mean arterial blood pressure | mean arterial blood pressure will be monitored at different times | within the duration of the operation |
| Pulmonary function tests | forced expiratory volume at one second | within the first 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| PaO2 | PaO2 will be monitored at different times | within the first 24 hours |
| Arterial to end-tidal PaCO2- difference | Arterial to end-tidal PaCO2- difference will be monitored at different times |
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Inclusion Criteria:
Exclusion Criteria:
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female patients only
female patients only
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| Name | Affiliation | Role |
|---|---|---|
| Sayed K Abd-Elshafy, M.D | Associate Profossor | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine | Asyut | Egypt |
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| ID | Term |
|---|---|
| D011027 | Pneumoperitoneum |
| ID | Term |
|---|---|
| D010532 | Peritoneal Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D010535 | Laparoscopy |
| ID | Term |
|---|---|
| D004724 | Endoscopy |
| D003949 | Diagnostic Techniques, Surgical |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| within the first 24 hours |
| Intra-abdominal pressure | Intra-abdominal pressure by direct measurement and indirect by Foley´s catheter will be monitored at different times (Cm water) | within the first 24 hours |
| Postoperative nausea and vomiting | Postoperative nausea and vomiting will be monitored at different times by special scale | within the first 24 hours |
| Analgesic requirement | Analgesic requirement will be monitored at different times by special scale (VAS) | within the first 24 hours |
| D019060 | Minimally Invasive Surgical Procedures |
| D013514 | Surgical Procedures, Operative |