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| Name | Class |
|---|---|
| The Ontario Spor Support Unit | OTHER |
| Canadian Institutes of Health Research (CIHR) | OTHER_GOV |
| Institute for Clinical Evaluative Sciences | OTHER |
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The aim of this study is to test a support program for older adults with symptoms of depression and other chronic health problems after they are discharged home from hospital. The study will be conducted in three communities in Ontario (Sudbury, Burlington, and Hamilton) and the program will be implemented with input from community members. The program will be delivered by a Registered Nurse, who will provide support to patients via home visits and telephone calls. The nurse's role will involve linking patients and their caregivers with needed services and supports, reviewing medications that the patients are taking, assessing patients' health, building the skills of patients in problem-solving and managing their care, and providing education to patients and their caregivers.
Implementing transitional care interventions for older adults with depressive symptoms and multiple chronic conditions (MCC) is a pressing concern since older adults with depression face persistent health disparities. The Community Assets Supporting Transitions (CAST) research team seeks to address these health inequities, and improve health outcomes in this vulnerable and under-served population by developing and implementing an intervention that will improve patients' self-management ability, support their families and caregivers, and build capacity for primary care and other health and non-health providers to collaborate in delivering home and community services. The proposed study builds on our pilot study that evaluated a nurse-led intervention for older adult home care clients with MCC and depressive symptoms and demonstrated that the intervention was feasible and effective in reducing depressive symptoms.
The overall aim of the study is to improve care transitions in older adults with MCC and depressive symptoms. The project will address three research questions:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group (CAST) | Experimental | Participants in the intervention group will receive the CAST hospital-to-home transition intervention in addition to usual care. |
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| Control group (usual care) | No Intervention | Participants assigned to the control group will receive usual care at discharge from hospital to home. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intervention group (CAST) | Behavioral | Intervention duration is expected to be 6 months. A full-time registered nurse (RN) will function as a Care Transitions Coordinator (CTC) who works collaboratively with one local hospital and other health and non-health representatives to deliver the intervention, which includes:
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| Measure | Description | Time Frame |
|---|---|---|
| Change in mental functioning of the older adult study participant | Measured by the mental component summary (MCS) score of the Veterans RAND 12 item Health Survey (VR-12). | T1 = Baseline data collection; T2 = 6 months after randomization; T3 = 12 months after randomization |
| Measure | Description | Time Frame |
|---|---|---|
| Change in mental functioning of the family/friend caregiver of older adult participant (if applicable). | Measured by the mental component summary (MCS) score of the Veterans RAND 12 item Health Survey (VR-12). | T1 = Baseline data collection; T2 = 6 months after randomization; T3 = 12 months after randomization |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Maureen F Markle-Reid, Ph.D. | McMaster University | Principal Investigator |
| Carrie McAiney, Ph.D. | University of Waterloo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Joseph Brant Hospital | Burlington | Ontario | Canada | |||
| Health Sciences North/Laurentian University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24886344 | Background | Markle-Reid M, McAiney C, Forbes D, Thabane L, Gibson M, Browne G, Hoch JS, Peirce T, Busing B. An interprofessional nurse-led mental health promotion intervention for older home care clients with depressive symptoms. BMC Geriatr. 2014 May 10;14:62. doi: 10.1186/1471-2318-14-62. | |
| 21867539 | Background | Markle-Reid MF, McAiney C, Forbes D, Thabane L, Gibson M, Hoch JS, Browne G, Peirce T, Busing B. Reducing depression in older home care clients: design of a prospective study of a nurse-led interprofessional mental health promotion intervention. BMC Geriatr. 2011 Aug 25;11:50. doi: 10.1186/1471-2318-11-50. |
| Label | URL |
|---|---|
| Ontario SPOR support unit | View source |
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| ID | Term |
|---|---|
| D003863 | Depression |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| Laurentian University |
| OTHER |
| The Labarge Optimal Aging Initiative | OTHER |
The proposed study design is a pragmatic randomized controlled trial (RCT). A pragmatic design applies RCT methodology in actual care settings to better inform decisions on the likely benefits, harms, and costs of real world implementation. The design is further classified as a Type II hybrid effectiveness-implementation study, which assigns equal weight to assessing program effectiveness and implementation.
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The Research Assistant who will be collecting the outcome measures will be blinded to group allocation (intervention vs. control) for the duration of data collection.
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| Change in physical function of the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). |
Measured by the physical component summary (PCS) score of the Veterans RAND 12 item Health Survey (VR-12). |
| T1 = Baseline data collection; T2 = 6 months after randomization; T3 = 12 months after randomization |
| Change in health-related quality of life of the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). | Measured by the Veterans RAND 12 item Health Survey (VR-12). | T1 = Baseline data collection; T2 = 6 months after randomization; T3 = 12 months after randomization |
| Change in depressive symptoms of the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). | As measured by the CESD-10 to determine the presence and severity of depressive symptoms. | T1 = Baseline data collection; T2 = 6 months after randomization; T3 = 12 months after randomization |
| Change in anxiety of the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). | As measured by the GAD-7 (24). | T1 = Baseline data collection; T2 = 6 months after randomization; T3 = 12 months after randomization |
| Change in caregiver strain of the family/friend caregiver of the older adult study participant (if applicable) | As measured by the Modified Caregiver Strain Index | T1 = Baseline data collection; TT2 = 6 months after randomization; T3 = 12 months after randomization |
| Change in utilization of health and social services by the: 1) older adult study participant, 2) family/friend caregiver of the older adult study participant. | As measured by the Health and Social Services Utilization Inventory | T1 = Baseline data collection; T2 = 6 months after randomization; T3 = 12 months after randomization |
| Change in utilization of health services by the older adult study participant | As identified through Institute for Clinical Evaluative Sciences (ICES) databases | T2 = 6 months after randomization; T3 = 12 months after randomization |
| Change in unmet care needs of the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). | As measured through the Unmet Care Needs questionnaire (developed using input from patient/caregiver co-researchers to ensure the inclusion of outcomes that are relevant and meaningful to patients and caregivers). | T1 = Baseline data collection; T2 = 6 months after randomization |
| Change in patient-provider communication of the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). | As measured through the Patient-Provider Communication (PCC) questionnaire. | T1 = Baseline data collection; T2 = 6 months after randomization |
| Change in patient-reported experience (CCCQ) for the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). | As measured through the adapted Client-Centred Care Questionnaired (CCCQ). | T1 = Baseline data collection; T2 = 6 months after randomization |
| Change in patient-reported experience (IC-PREMs) for the: 1) older adult study participant, 2) family/friend caregiver of older adult participant (if applicable). | As measured through the adapted Integrated Care Patient-Reported Experience Measures (IC-PREMs). | T1 = Baseline data collection; T2 = 6 months after randomization |
| Greater Sudbury |
| Ontario |
| Canada |
| Hamilton General Hospital | Hamilton | Ontario | L8L 2X2 | Canada |
| School of Nursing, McMaster University | Hamilton | Ontario | L8N 3Z5 | Canada |
| 34310640 | Derived | Markle-Reid M, McAiney C, Fisher K, Ganann R, Gauthier AP, Heald-Taylor G, McElhaney JE, McMillan F, Petrie P, Ploeg J, Urajnik DJ, Whitmore C. Effectiveness of a nurse-led hospital-to-home transitional care intervention for older adults with multimorbidity and depressive symptoms: A pragmatic randomized controlled trial. PLoS One. 2021 Jul 26;16(7):e0254573. doi: 10.1371/journal.pone.0254573. eCollection 2021. |
| 32650732 | Derived | Markle-Reid M, McAiney C, Ganann R, Fisher K, Gafni A, Gauthier AP, Heald-Taylor G, McElhaney J, Ploeg J, Urajnik DJ, Valaitis R, Whitmore C. Study protocol for a hospital-to-home transitional care intervention for older adults with multiple chronic conditions and depressive symptoms: a pragmatic effectiveness-implementation trial. BMC Geriatr. 2020 Jul 10;20(1):240. doi: 10.1186/s12877-020-01638-0. |