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The purpose of this study is to evaluate whether carotid Doppler peak systolic velocity can be an easy to measure possible surrogate for echocardiographic measurement of aortic peak systolic velocity variation which is an index of fluid responsiveness in mechanically ventilated children intra-operatively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental | Children aged 1-12 years undergoing major surgeries under general endotracheal anaesthesia with mechanical ventilation under neuromuscular blockade |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Measurement of aortic and carotid Doppler peak systolic velocity variation | Other | Aortic peak systolic velocity variation to be measured by echocardiography from apical five chamber and suprasternal windows alongwith carotid peak systolic velocity variation by Doppler ultrasound simultaneously at intermittent time points intermittently. |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation | Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation by Bland-Altman analysis | Measurements made within 3 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows | Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows by Bland-Altman analysis | Measurements made within 3 minutes |
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Inclusion Criteria:
• Patients scheduled for mon-cardiac surgeries under general endotracheal anaesthesia in supine position with expected duration more than 1 hour
Exclusion Criteria:
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Eligible patients consenting for inclusion
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| Name | Affiliation | Role |
|---|---|---|
| Subhrashis Guha Niyogi, MBBS | Junior Resident | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Postgraduate Institute of Medical Education & Research | Chandigarh | 160012 | India |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31811550 | Derived | Niyogi SG, Sen IM, Jayant A, Mandal B, Bhardwaj N, Yaddanapudi S, Mathew P. Surrogate indices of aortic peak systolic velocity variation to monitor fluid responsiveness in pediatric non-cardiac surgery: a prospective observational study. J Clin Monit Comput. 2020 Dec;34(6):1159-1166. doi: 10.1007/s10877-019-00431-8. Epub 2019 Dec 7. |
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