The Effect of In-vitro Myoinositol Supplementation of Human Sperm on the Outcome of Cryopreservation

The Effect of In-vitro Myoinositol Supplementation of Human Sperm on the Outcome of Cryopreservation

The objective of this study is to evaluate the effect of in-vitro myoinositol supplementation of human sperm on the outcome of cryopreservation.

Sperm cryopreservation is considered the most valuable and used way to preserve male reproductive function. Unfortunately, osmotic effects of freezing and thawing during the cryopreservation process negatively affect sperm morphology and motility .

Myoinositol is the most biologically important form of inositol in nature. In male reproductive system, myoinositol appears to regulate sperm motility, capacitation and acrosomal reaction.

The objective of this study is to evaluate the effect of in-vitro myoinositol supplementation of human sperm on the outcome of cryopreservation.

Inclusion Criteria:

• Infertile men with normal or abnormal semen analysis

Exclusion Criteria:

• Azoospermic samples