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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A00042-45 | Other Identifier | 2014-A00042-45 |
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An increase in intracranial pressure (ICP) during migraine attacks is possible and could contribute to pain initiation and maintenance. From now on, it was not possible to measure ICP in a non-invasive way. The development of a new tool allows non-invasive self-measures of ICP variations. Thus, it is possible for the first time to look for such ICP variations during migraine attacks and to conclude if this mechanism is implied in the pathophysiology of migraine.
Womens presenting with regular menstrual migraine treated with triptans will be included in the study. Self-measure of ICP will be performed outside and during menstrual migraine attacks. The potential variations will be compared to the measures done on matched healthy women outside and during menses.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women with menstrual migraine | Womens presenting with regular menstrual migraine treated with triptans will be included in the study. |
| |
| Matched control | The potential variations will be compared to the measures done on matched healthy women outside and during menses. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intracranial pressure variations | Other | Self-measure of ICP will be performed outside and during menstrual migraine attacks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intracranial pressure variations | Measured during menstrual migraine attacks compared to ICP in non-migraine days and in matched healthy women | during menstrual migraine attacks |
| Measure | Description | Time Frame |
|---|---|---|
| Relationships between ICP variations and clinical parameters | Age, BMI, pain intensity, pulsating pain, allodynia, nausea, photophobia, phonophobia, dizziness, tinnitus | during menstrual migraine attacks |
| Relationships between ICP variations and pain relief |
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Inclusion Criteria:
Exclusion Criteria:
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Womens presenting with regular menstrual migraine treated with triptans will be included in the study. Self-measure of ICP will be performed outside and during menstrual migraine attacks. The potential variations will be compared to the measures done on matched healthy women outside and during menses.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Patrick LACARIN | Contact | 04 73 75 11 95 | placarin@chu-clermontferrand.fr | |
| Pierre CLAVELOU | Contact | pclavelou@chu-clermontferrand.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Clermont-Ferrand | Recruiting | Clermont-Ferrand | Auvergne | 63003 | France |
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| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| D006261 | Headache |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| during menstrual migraine attacks |
| D009422 | Nervous System Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |